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Flaws emerge in modeling human genetic diseases in animals

  • Written by Gage Crump, Professor of Stem Cell Biology and Regenerative Medicine, University of Southern California
Flaws emerge in modeling human genetic diseases in animalsThis confocal microscope image shows the face of a week-old zebrafish.Peter Fabian and Gage Crump, CC BY-NC

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance to human...

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