Hepatitis B shot for newborns has nearly eliminated childhood infections with this virus in the US
- Written by David Higgins, Assistant Professor of Pediatrics, University of Colorado Anschutz Medical Campus

Some newborns were exposed when their mothers weren’t properly screened or if their mothers got infected late in pregnancy. Children also became infected through household contacts[16] or in child care settings by exposures as ordinary as shared toothbrushes or a bite that breaks the skin. Because hepatitis B can survive for a week[17] on household surfaces, and many carriers are unaware they are infected, even babies and toddlers of uninfected mothers remained at risk.
Recognizing these gaps, in 1991 the CDC recommended hepatitis B vaccination for every child starting at birth[18], regardless of maternal risk.
Vaccinating at birth
The greatest danger for infants contracting hepatitis B is at birth, when contact with a mother’s blood can transmit the virus. Without preventive treatment or vaccination, 70% to 90% of infants born to infected mothers will become infected themselves, and 90% of those infections will become chronic[19]. The infection in these children silently damages their liver, potentially leading to liver cancer and death[20].
About 80% of parents choose to follow[21] the CDC’s guidance and vaccinate their babies at birth. If the CDC’s recommendations change to delaying the first dose to 1 month old, it would leave babies unprotected during this most vulnerable window, when infection is most likely to lead to chronic infection[22] and silently damage the liver.
The hepatitis B vaccines used in the U.S. have an outstanding safety record. The only confirmed risk is an allergic reaction called anaphylaxis that occurs in roughly 1 in 600,000 doses[23], and no child has died from such a reaction. Extensive studies show no link to other serious conditions[24].
The current recommendations are designed to protect every child, including those who slip through gaps in maternal screening or encounter the virus in everyday life. A reversion to the ineffective risk-based approach threatens to erode this critical safety net.
References
- ^ CC BY-ND (creativecommons.org)
- ^ 18,000 children every year contracted the virus before their 10th birthday (doi.org)
- ^ die prematurely from cirrhosis or liver cancer (www.cdc.gov)
- ^ fewer than 1,000 (www.cdc.gov)
- ^ Fewer than 20 babies (www.cdc.gov)
- ^ pediatrician and preventive medicine specialist (som.cuanschutz.edu)
- ^ most evidence-based ways to keep American children free (doi.org)
- ^ Advisory Committee on Immunization Practices (www.cdc.gov)
- ^ scheduled for Oct. 22-23 (www.cdc.gov)
- ^ disbanded the entire committee (theconversation.com)
- ^ procedures are not being followed (thehill.com)
- ^ blood and bodily fluids (www.mayoclinic.org)
- ^ available since the early 1980s (www.hepb.org)
- ^ only if they were at high risk of being infected (www.cdc.gov)
- ^ Ekkasit Jokthong/iStock via Getty Images Plus (www.gettyimages.com)
- ^ infected through household contacts (www.cdc.gov)
- ^ survive for a week (www.healthline.com)
- ^ recommended hepatitis B vaccination for every child starting at birth (www.cdc.gov)
- ^ 90% of those infections will become chronic (www.cdc.gov)
- ^ liver cancer and death (doi.org)
- ^ 80% of parents choose to follow (www.cdc.gov)
- ^ most likely to lead to chronic infection (doi.org)
- ^ that occurs in roughly 1 in 600,000 doses (www.cdc.gov)
- ^ other serious conditions (doi.org)
Authors: David Higgins, Assistant Professor of Pediatrics, University of Colorado Anschutz Medical Campus