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How mRNA vaccines from Pfizer and Moderna work, why they're a breakthrough and why they need to be kept so cold

  • Written by Sanjay Mishra, Project Coordinator & Staff Scientist, Vanderbilt University Medical Center, Vanderbilt University
How mRNA vaccines from Pfizer and Moderna work, why they're a breakthrough and why they need to be kept so coldModerna's new mRNA vaccine is almost 94.5% effective in large-scale trials.JUSTIN TALLIS/AFP via Getty Images

As the weather cools, the number of infections of the COVID-19 pandemic are rising sharply. Hamstrung by pandemic fatigue, economic constraints and political discord, public health officials have struggled to control the surging pandemic....

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